The major product formed in the following reaction sequence is

F2 Madhuri Teaching 27.03.2023 D89

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CSIR-UGC (NET) Chemical Science: Held on (26 Nov 2020)
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Option 2 : F2 Madhuri Teaching 27.03.2023 D91
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Concept:

  • Organolithium reagents contain carbon–lithium (C-Li) bonds. 
  • The large difference in electronegativity between the carbon atom and the lithium atom results in highly ionic Carbon−Lithium bonds.
  • Because of the polar nature of the C−Li bond, organolithium reagents can act as good nucleophiles as well as strong bases.

Explanation:

  • The reaction pathway is shown below:

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  • From the above reaction, we see that in the first step, the organolithium reagent (tBuLi) will act as a strong base and will abstract an acidic -H from the pyridine derivative.
  • In the last step of the reaction, the resulting carbanion will react with the generated I2 in the reaction medium to give the final product.
  • In the reaction medium ICH2CH2I will form I2.

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Conclusion:

  • Hence, the major product formed in the following reaction sequence is

F2 Madhuri Teaching 27.03.2023 D91.

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